Channel gating: Twist to open
نویسندگان
چکیده
منابع مشابه
Channel gating: Twist to open
Recent studies of the bacterial mechanosensitive channel MscL have combined a number of different approaches to come up with a model for the channel gating mechanism.
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Kinetics of single voltage-dependent Shaker potassium channels expressed in Xenopus oocytes were studied in the absence of fast N-type inactivation. Comparison of the single-channel first latency distribution and the time course of the ensemble average current showed that the activation time course and its voltage dependence are largely determined by the transitions before first opening. The op...
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P otassium channels are highly complex molecular systems that modulate the cell potential in response to extracellular or intracellular signals. In multicellular organisms, K currents are essential to electrical signaling, governing central nervous system, cardiac, renal, and a host of other organ functions. Publication of the first K channel structure in 1998 (1) represented a landmark in our ...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2001
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(01)00195-6